Priscilla is a native of Navasota, Texas and continues to reside there with her husband Don, a CPA. They have been married 39 years and are the parents of a daughter, Nancy Jane Otto, of Houston, and son William Otto, who along with his wife, Tara and daughter Campbell also live in Houston. Their first child, Edward Lee, passed away in 1974 from neuroblastoma, a rare form of early childhood cancer. Priscilla graduated from Texas Tech University in elementary education and has spent the majority of her career teaching sixth grade. She has taught in Austin ISD, Houston ISD, Grace Presbyterian School and Brenham Christian Academy. She has served on a number of boards including the American Cancer Society, Texas A&M's Pi Beta Phi Advisory Board, City of Navasota Parks and Recreation Board, and First Presbyterian Church of Navasota Elder Board. Her hobbies include wood carving and fly fishing.